Rolf Brekken : rechercher sur Z-Library

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1

Pancreatic cancer stroma: an update on therapeutic targeting strategies

Hosein, Abdel N., Brekken, Rolf A., Maitra, Anirban

Journal:

Nature Reviews Gastroenterology and Hepatology (formerly Nature Clinical Practice Gastroenterology and Hepatology)

Année:

2020

Fichier:

PDF, 7.48 MB

2020

2

SPARC, a matricellular protein: at the crossroads of cell–matrix communication: [Matrix Biology (2000) 569–580]

Rolf A. Brekken, E.Helene Sage

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 634 KB

english, 2001

3

Nintedanib, a triple angiokinase inhibitor, enhances cytotoxic therapy response in pancreatic cancer

Awasthi, Niranjan, Hinz, Stefan, Brekken, Rolf A., Schwarz, Margaret A., Schwarz, Roderich E.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2015

4

[Biology of Extracellular Matrix] Extracellular Matrix in Tumor Biology || The Extracellular Matrix of Tumors: A Focus on Fibronectin and Fibulin-5

Brekken, Rolf A., Stupack, Dwayne

Année:

2017

Langue:

english

Fichier:

PDF, 366 KB

english, 2017

5

[IEEE 2017 IEEE International Ultrasonics Symposium (IUS) - Washington, DC (2017.9.6-2017.9.9)] 2017 IEEE International Ultrasonics Symposium (IUS) - Monitoring early tumor response to vascular targeted therapy using super-resolution ultrasound imaging

Ghosh, Debabrata, Xiong, Fangyuan, Sirsi, Shashank R, Mattrey, Robert, Brekken, Rolf, Kim, Jung-Whan, Hoyt, Kenneth

Année:

2017

Langue:

english

Fichier:

PDF, 612 KB

english, 2017

6

Design, Synthesis and Biological Evaluation of 3-(Imidazo[1,2-a]pyrazin-3-ylethynyl)-4-isopropyl-N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as Dual Inhibitors of Discoidin Domain Receptor 1 and 2 (DDR1/2)

Wang, Zhen, Zhang, Yali, Pinkas, Daniel, Fox, Alice, Luo, Jinfeng, Huang, Huocong, Cui, Shengyang, Xiang, Qiuping, Xu, Tingting, Xun, Qiuju, zhu, Dongsheng, Tu, Zheng-Chao, Ren, Xiaomei, Brekken, Rolf

Journal:

Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2018

7

Hypoxia-induced autophagy of stellate cells inhibits expression and secretion of lumican into microenvironment of pancreatic ductal adenocarcinoma

Li, Xinqun, Lee, Yeonju, Kang, Ya’an, Dai, Bingbing, Perez, Mayrim Rios, Pratt, Michael, Koay, Eugene J., Kim, Michael, Brekken, Rolf A., Fleming, Jason B.

Journal:

Cell Death & Differentiation

Année:

2018

Langue:

english

Fichier:

PDF, 3.74 MB

english, 2018

8

The angiogenic “vascular endothelial growth factor/flk-1(KDR) receptor” pathway in patients with endometrial carcinoma : Prognostic and therapeutic implications

Alexandra Giatromanolaki, Efthimios Sivridis, Rolf Brekken, Philip E. Thorpe, Panagiotis Anastasiadis, Kevin C. Gatter, Adrian L. Harris, Michael I. Koukourakis

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 657 KB

english, 2001

9

Intravenous delivery of the plasma fraction of stored packed erythrocytes promotes pancreatic cancer growth in immunocompetent mice

Carlton C. Barnett Jr, Adam W. Beck, Shane E. Holloway, Marguerite Kehler, Marie K. Schluterman, Rolf A. Brekken, Jason B. Fleming, Christopher C. Silliman

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 762 KB

english, 2010

10

Strategies for vascular targeting in tumors

Rolf A. Brekken, Chenggang Li, Shant Kumar

Journal:

International Journal of Cancer

Année:

2002

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2002

11

Combination of a monoclonal anti-phosphatidylserine antibody with gemcitabine strongly inhibits the growth and metastasis of orthotopic pancreatic tumors in mice

Adam W. Beck, Troy A. Luster, Andrew F. Miller, Shane E. Holloway, Chris R. Conner, Carlton C. Barnett, Philip E. Thorpe, Jason B. Fleming, Rolf A. Brekken

Journal:

International Journal of Cancer

Année:

2006

Langue:

english

Fichier:

PDF, 277 KB

english, 2006

12

The effects of aging on tumor growth and angiogenesis are tumor-cell dependent

May J. Reed, Nathan Karres, Daniel Eyman, Abigail Cruz, Rolf A. Brekken, Stephen Plymate

Journal:

International Journal of Cancer

Année:

2007

Langue:

english

Fichier:

PDF, 479 KB

english, 2007

13

Anti-VEGF-A therapy reduces lymphatic vessel density and expression of VEGFR-3 in an orthotopic breast tumor model

Brandt Whitehurst, Michael J. Flister, Juhi Bagaitkar, Lisa Volk, Christopher M. Bivens, Brent Pickett, Emely Castro-Rivera, Rolf A. Brekken, Robert D. Gerard, Sophia Ran

Journal:

International Journal of Cancer

Année:

2007

Langue:

english

Fichier:

PDF, 991 KB

english, 2007

14

Functional imaging of angiogenesis in an orthotopic model of pancreatic cancer

Jason B. Fleming, Rolf A. Brekken

Journal:

Journal of Cellular Biochemistry

Année:

2003

Langue:

english

Fichier:

PDF, 565 KB

english, 2003

15

SPARC regulates TGF-beta1-dependent signaling in primary glomerular mesangial cells

Aleksandar Francki, Timothy D. McClure, Rolf A. Brekken, Kouros Motamed, Carrie Murri, Tongwen Wang, E. Helene Sage

Journal:

Journal of Cellular Biochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 323 KB

english, 2004

16

A peptoid antagonist of VEGF Receptor 2 recognizes a ‘hotspot’ in the extracellular domain distinct from the hormone-binding site

D. Gomika Udugamasooriya, Caroline Ritchie, Rolf A. Brekken, Thomas Kodadek

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 841 KB

english, 2008

17

The pharmacophore of a peptoid VEGF receptor 2 antagonist includes both side chain and main chain residues

D. Gomika Udugamasooriya, Geoff Dunham, Caroline Ritchie, Rolf A. Brekken, Thomas Kodadek

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 197 KB

english, 2008

18

Targeting vascular endothelium with avidin microbubbles

Grzegorz Korpanty, Paul A. Grayburn, Ralph V. Shohet, Rolf A. Brekken

Journal:

Ultrasound in Medicine & Biology

Année:

2005

Langue:

english

Fichier:

PDF, 155 KB

english, 2005

19

Immunotargeting of tumor vessels for cancer therapy

Claudia Gottstein, Xianming Huang, Boning Gao, Grietje Molema, Steve King, Rolf Brekken, Philip Thorpe

Journal:

Immunology Letters

Année:

1997

Langue:

english

Fichier:

PDF, 186 KB

english, 1997

20

Increased fibrovascular invasion of subcutaneous polyvinyl alcohol sponges in SPARC-null mice

AMY D. BRADSHAW, MAY J. REED, JULIET G. CARBON, EMMETT PINNEY, ROLF A. BREKKEN, E. HELENE SAGE

Journal:

Wound Repair and Regeneration

Année:

2001

Langue:

english

Fichier:

PDF, 4.87 MB

english, 2001

21

Smac mimetic-derived augmentation of chemotherapeutic response in experimental pancreatic cancer

Niranjan Awasthi, Amanda Kirane, Margaret A Schwarz, Jason E Toombs, Rolf A Brekken, Roderich E Schwarz

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 974 KB

english, 2011

22

The angiogenic pathway ‘vascular endothelial growth factor/flk-1(KDR)-receptor’ in rheumatoid arthritis and osteoarthritis

Alexandra Giatromanolaki, Efthimios Sivridis, Nick Athanassou, Emmanuel Zois, Philip E. Thorpe, Rolf A. Brekken, Kevin C. Gatter, Adrian L. Harris, Ioannis M. Koukourakis, Michael I. Koukourakis

Journal:

The Journal of Pathology

Année:

2001

Langue:

english

Fichier:

PDF, 306 KB

english, 2001

23

The regulatory function of SPARC in vascular biology

Lee B. Rivera, Amy D. Bradshaw, Rolf A. Brekken

Journal:

Cellular and Molecular Life Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 335 KB

english, 2011

24

Accumulation of Pro-Cancer Cytokines in the Plasma Fraction of Stored Packed Red Cells

Douglas D. Benson, Adam W. Beck, Marie S. Burdine, Rolf Brekken, Christopher C. Silliman, Carlton C. Barnett

Journal:

Journal of Gastrointestinal Surgery

Année:

2012

Langue:

english

Fichier:

PDF, 400 KB

english, 2012

25

SPARC: a matricellular regulator of tumorigenesis

Shanna A. Arnold, Rolf A. Brekken

Journal:

Journal of Cell Communication and Signaling

Année:

2009

Langue:

english

Fichier:

PDF, 563 KB

english, 2009

26

Fibulin-5, an integrin-binding matricellular protein: its function in development and disease

Hiromi Yanagisawa, Marie K. Schluterman, Rolf A. Brekken

Journal:

Journal of Cell Communication and Signaling

Année:

2009

Langue:

english

Fichier:

PDF, 383 KB

english, 2009

27

10.1038/35036374

Hanahan, Douglas, Bergers, Gabriele, Brekken, Rolf, McMahon, Gerald, Vu, Thiennu H., Itoh, Takeshi, Tamaki, Kazuhiko, Tanzawa, Kazuhiko, Thorpe, Philip, Itohara, Shigeyoshi, Werb, Zena

Journal:

Nature Cell Biology

Année:

2000

Langue:

english

Fichier:

PDF, 919 KB

english, 2000

28

Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo

Brantley, Dana M, Cheng, Nikki, Thompson, Erin J, Lin, Qing, Brekken, Rolf A, Thorpe, Philip E, Muraoka, Rebecca S, Cerretti, Douglas Pat, Pozzi, Ambra, Jackson, Dowdy

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 916 KB

english, 2002

29

Tumor specific activation of the VEGF/KDR angiogenic pathway in a subset of locally advanced squamous cell head and neck carcinomas

Alexandra Giatromanolaki, Michael I. Koukourakis, Efthimios Sivridis, Philip E. Thorpe, Rolf A. Brekken, Simopoulos Konstantinos, George Fountzilas, Kevin C. Gatter, Adrian L. Harris

Journal:

Clinical and Experimental Metastasis

Année:

2000

Langue:

english

Fichier:

PDF, 90 KB

english, 2000

30

Selective Blockade of Vascular Endothelial Growth Factor Receptor 2 With an Antibody Against Tumor-Derived Vascular Endothelial Growth Factor Controls the Growth of Human Pancreatic Adenocarcinoma Xenografts

Shane E. Holloway, Adam W. Beck, Latha Shivakumar, Jessica Shih, Jason B. Fleming, Rolf A. Brekken

Journal:

Annals of Surgical Oncology

Année:

2006

Langue:

english

Fichier:

PDF, 428 KB

english, 2006

31

Secreted protein acidic and rich in cysteine as a regulator of murine ovarian cancer growth and chemosensitivity

Shawna L. Bull Phelps, Juliet Carbon, Andrew Miller, Emely Castro-Rivera, Shanna Arnold, Rolf A. Brekken, Jayanthi S. Lea

Journal:

American Journal of Obstetrics and Gynecology

Année:

2009

Langue:

english

Fichier:

PDF, 409 KB

english, 2009

32

Increased expression of Cyr61 (CCN1) identified in peritoneal metastases from human pancreatic cancer

Shane E. Holloway, Adam W. Beck, Luc Girard, M. Raffat Jaber, Carlton C. Barnett Jr, Rolf A. Brekken, Jason B. Fleming

Journal:

Journal of the American College of Surgeons

Année:

2005

Langue:

english

Fichier:

PDF, 285 KB

english, 2005

33

Role of VEGF-A in Vascularization of Pancreatic Islets

Eckhard Lammert, Guqiang Gu, Margaret McLaughlin, Dennis Brown, Rolf Brekken, Lewis Charles Murtaugh, Hans-Peter Gerber, Napoleone Ferrara, Douglas A. Melton

Journal:

Current Biology

Année:

2003

Langue:

english

Fichier:

PDF, 377 KB

english, 2003

34

GU81, a VEGFR2 antagonist peptoid, enhances the anti-tumor activity of doxorubicin in the murine MMTV-PyMT transgenic model of breast cancer

Kristi D Lynn, D Gomika Udugamasooriya, Christina L Roland, Diego H Castrillon, Thomas J Kodadek, Rolf A Brekken

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 6.26 MB

english, 2010

35

The Adnectin CT-322 is a novel VEGF receptor 2 inhibitor that decreases tumor burden in an orthotopic mouse model of pancreatic cancer

Sean P Dineen, Laura A Sullivan, Adam W Beck, Andrew F Miller, Juliet G Carbon, Roni Mamluk, Henry Wong, Rolf A Brekken

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 2.78 MB

english, 2008

36

A Peptoid “Antibody Surrogate” That Antagonizes VEGF Receptor 2 Activity

Udugamasooriya, D. Gomika, Dineen, Sean P., Brekken, Rolf A., Kodadek, Thomas

Journal:

Journal of the American Chemical Society

Année:

2008

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2008

37

Expression of Soluble VEGF Receptor 2 and Characterization of Its Binding by Surface Plasmon Resonance

Xianming Huang, Claudia Gottstein, Rolf A. Brekken, Philip E. Thorpe

Journal:

Biochemical and Biophysical Research Communications

Année:

1998

Langue:

english

Fichier:

PDF, 154 KB

english, 1998

38

49. SMAC Mimetic JP-1201, in Combination With TRAIL or Gemcitabine, Is a Potent Inhibitor of Pancreatic Tumor Growth and Metastasis in a Preclinical Model of Pancreatic Cancer

Sean Dineen, Lin Li, Haizhou Sun, Juliet Carbon, Bert Pronk, Rolf Brekken

Journal:

Journal of Surgical Research

Année:

2008

Langue:

english

Fichier:

PDF, 49 KB

english, 2008

39

147. The Acellular Fraction of Stored Platelets Promotes Cancer Invasion

Sean P. Dineen, Christopher C. Silliman, Jason E. Toombs, Christina L. Roland, Rolf A. Brekken, Carlton C. Barnett Jr.

Journal:

Journal of Surgical Research

Année:

2008

Langue:

english

Fichier:

PDF, 279 KB

english, 2008

40

QS100. An In Vivo Selection Model Identifies Molecular Changes Necessary for Liver Metastasis From Pancreatic Cancer

Jason B. Fleming, Yaan Kang, Sean Dineen, Rolf A. Brekken

Journal:

Journal of Surgical Research

Année:

2008

Langue:

english

Fichier:

PDF, 227 KB

english, 2008

41

QS314. Tumor Associated Macrophage Profile Reflects the Efficacy of Therapy in Pancreatic Cancer

Jason B. Fleming, Sean Dineen, Shane E. Holloway, Andrew F. Miller, Rolf A. Brekken

Journal:

Journal of Surgical Research

Année:

2008

Langue:

english

Fichier:

PDF, 87 KB

english, 2008

42

The Acellular Fraction of Stored Platelets Promotes Tumor Cell Invasion

Sean P. Dineen, Christina L. Roland, Jason E. Toombs, Marguerite Kelher, Christopher C. Silliman, Rolf A. Brekken, Carlton C. Barnett Jr.

Journal:

Journal of Surgical Research

Année:

2009

Langue:

english

Fichier:

PDF, 596 KB

english, 2009

43

Fibulin-5 inhibits integrin-induced ROS production

Marie K. Schluterman, Shelby L. Chapman, Grzegorz Korpanty, Hiromi Yanagisawa, Rolf A. Brekken

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 66 KB

english, 2008

44

SPARC regulates inhibition of pericyte migration by TGF-beta

Lee B. Rivera, Shanna A. Arnold, Rolf A. Brekken

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 60 KB

english, 2008

45

SPARC influences collagen interaction with the cell surface

Yuhua Zhang, Lee B. Rivera, Rolf A. Brekken, Amy D. Bradshaw

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 61 KB

english, 2008

46

TGFβ1 enhances pancreatic tumor progression in SPARC-null mice

Shanna A. Arnold, Lee B. Rivera, Juliet G. Carbon, Sean P. Dineen, Amy D. Bradshaw, Rolf A. Brekken

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 63 KB

english, 2008

47

TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation

Yi-Hung Ou, Michael Torres, Rosalyn Ram, Etienne Formstecher, Christina Roland, Tzuling Cheng, Rolf Brekken, Ryan Wurz, Andrew Tasker, Tony Polverino, Seng-Lai Tan, Michael A. White

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.77 MB

english, 2011

48

Compromised Production of Extracellular Matrix in Mice Lacking Secreted Protein, Acidic and Rich in Cysteine (SPARC) Leads to a Reduced Foreign Body Reaction to Implanted Biomaterials

Pauli Puolakkainen, Amy D. Bradshaw, Themistoklis R. Kyriakides, May Reed, Rolf Brekken, Thomas Wight, Paul Bornstein, Buddy Ratner, E. Helene Sage

Journal:

The American Journal of Pathology

Année:

2003

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2003

49

The matricellular protein SPARC is expressed in human trabecular meshwork

Douglas J. Rhee, Robert N. Fariss, Rolf Brekken, E. Helene Sage, Paul Russell

Journal:

Experimental Eye Research

Année:

2003

Langue:

english

Fichier:

PDF, 239 KB

english, 2003

50

SPARC-like 1 Regulates the Terminal Phase of Radial Glia-Guided Migration in the Cerebral Cortex

Vik Gongidi, Colleen Ring, Matt Moody, Rolf Brekken, E.Helene Sage, Pasko Rakic, E.S. Anton

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 742 KB

english, 2004